We explored how three popular tools—Blender, Unity and Unreal Engine—can help scientists create detailed 3D visuals of cells and biological processes. Our study highlights how Blender excels in making highly accurate static models, Unity supports real-time simulations and Unreal Engine provides stunning visual quality for large-scale data. By comparing these platforms, we aim to guide researchers in choosing the right tool for their projects. This work emphasizes how 3D visualization can make complex biological concepts more accessible, improving both research and education.