The Undergraduate Research Journal
The Journal of Young Investigators would like to recognize the best of 2018 in a yearly print edition.
Submit your graphical and written abstracts for our abstract competition.
Submit photos and artwork to be featured on the cover.
Infections caused by H. pylori are associated with multiple gastrointestinal diseases. To effectively reduce disease-related morbidity is to ensure the absolute eradication of the organism. The stomach plays a vital role in endowing survival strategies to H. pylori by inducing stress-hardening and cross-resistance, which helps them resist the acidic gastric ecosystem and administered antibiotics, respectively. An unstable gastric pH can cause phenotypic alteration, which induces a non-proliferative state in the bacteria, makes them refractory to antibiotics.
Etheostoma is a genus of North American darter fish whose species have similar habitats and breeding seasons, yet hybridization is rare. Behavioral barriers have been demonstrated to play a key role in maintaining species boundaries. Further, conspecific (same species) sperm precedence has also been observed when the gametes of two different species come into contact. In this study, we investigated if physical characteristics of sperm could be a mechanism for the lower fertilization success of heterospecific (different species) males when eggs are simultaneously exposed to conspecific and heterospecific sperm. We chose to examine the sperm of two closely related species, E. zonale and E. barrenense.
Video games are a popular form of entertainment. But can video games have a negative impact on your focus? Many studies show that both duration of exposure and level of violence of video games appear to be associated with concentration difficulties. However, whilst much attention has been given to the affects of long duration of game playing to violent video games (1), little is known on the impact that short exposure to less violent video games can have. Jacob Brawer, a Clinical Neuroscience Research Intern at David Geffen School of Medicine at UCLA, has just published a study in the Journal of Young Investigators (JYI) providing the first evidence that even short-term video gaming can significantly impact both the concentration and attention of players (2)
The Nobel Prize in Medicine and Physiology for 2018 was awarded to Dr. James P. Allison and Dr. Tasuku Honjo for making breakthrough discoveries on strategies for treating cancer by preventing the “ignorance” of tumors by the immune system. Developing cancer cells are normally detected by surveying white blood cells, or T-lymphocytes, that recognize the tumor progenitors as abnormal and target the abnormal cells for destruction. However, as a tumor develops, the cancer cells of the tumor begin to send inhibitory signals to immune cells, causing them to “ignore” the growing tumor until it is virtually invisible to the immune system.
Dr. Longen Zhou is the director of Translational Cancer Research at Johnson & Johnson’s Shanghai headquarters. He has had extensive experience in the area of cancer drug development and working in the industrial sector. Dr. Zhou is very knowledgeable about various topics in health science and medicine. His work involves drugs targeting a variety of different cancers, including but not limited to lung cancer, stomach cancer, and leukemia. He has shared with JYI his insights about working in the field of drug development.
Rice has always been a versatile tool. From its use as a primitive form of cement when building the Great Wall of China, to providing nearly 20% of modern global caloric intake and acting as the main food source for 3 billion people worldwide, it has been an irreplaceable staple for humans for centuries. There are thousands of varieties of rice, but they are all in danger from the overwhelming threat of climate change (Ricepedia, 2018).
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