Acquired immuno deficiency syndrome is a disease that manifests itself as a result of gene silencing and changing gene patterns caused by human immuno virus infection. Inspite of sustained efforts by the scientific community, a permanent treatment method for this infection has not been formulated till date. With the advancements in stem cell research, animal cell culture and genetic engineering, it is possible to devise a treatment for human immuno virus Infection. This article gives an insight into the convergence of the above mentioned technologies to yield a technique called Chromosome Engineering', which might be a viable treatment option for human immuno virus and other retroviral infections.
The molecular basis for cell migration during morphogenesis has been a topic of intense interest and has yet to be fully understood. It is shown here how it is possible to construct a matrix to reflect different types of morphological changes associated with the "mass movements" which occur in Drosophila embryological development. It is also shown how this matrix can be correlated to a data from a time course microarray, to determine genes most correlated to their corresponding morphological change. Application of this method represents a novel methodology for discovering function for genes of unknown function.