"We must sail sometimes with the wind and sometimes against it', said Oliver Wendell Holmes, 'but we must sail, and not drift, nor lie at anchor'. So with man's epic voyage into space - a voyage the United States of America has led and still shall lead."
Acquired immuno deficiency syndrome is a disease that manifests itself as a result of gene silencing and changing gene patterns caused by human immuno virus infection. Inspite of sustained efforts by the scientific community, a permanent treatment method for this infection has not been formulated till date. With the advancements in stem cell research, animal cell culture and genetic engineering, it is possible to devise a treatment for human immuno virus Infection. This article gives an insight into the convergence of the above mentioned technologies to yield a technique called Chromosome Engineering', which might be a viable treatment option for human immuno virus and other retroviral infections.
The molecular basis for cell migration during morphogenesis has been a topic of intense interest and has yet to be fully understood. It is shown here how it is possible to construct a matrix to reflect different types of morphological changes associated with the "mass movements" which occur in Drosophila embryological development. It is also shown how this matrix can be correlated to a data from a time course microarray, to determine genes most correlated to their corresponding morphological change. Application of this method represents a novel methodology for discovering function for genes of unknown function.