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Compacting DNA: real-time imaging of condensing in action

Compacting DNA: real-time imaging of condensing in action

Proteins are often intuitively named after their function, and condensin is no exception. It condenses DNA inside the nucleus of a cell into X-shaped chromosomes for cell division. The name, however, provides no insight into how this feat is achieved. In fact, the molecular mechanism of how condensin organizes DNA inside the nucleus has previously only been hypothesized to involve extruding DNA into large loops.