Current Issue: January 2019
Most spinal cord injuries have an almost immediate and devastating effect on the person’s motor control. These severe impairments result from the interrupted communication between the brain and spinal cord, which deprives the spinal cord below the injury of instructions from the higher-level executive functions in the body. Without the essential sources of direction and excitement from the brain, the parts coordinated below the injury on the spinal cord face severe motor deficits – often complete or partial paralysis.
Glycation is the process whereby an enzyme catalyzes the bonding of a sugar molecule to another molecule, which can alter and inhibit cancer cell growth. Dr. Chan-Sik Kim from the Korea Institute of Oriental Medicine concluded in 2017 that preventing the glycation process and removing glycation products from the human body slows down aging.
Glycation as an endogenous process may alter the structure and biological functions of macromolecules, thus playing an important role in cell growth retardation. This study was conducted to evaluate the levels of glycation precursors, advanced glycation end products, and cell viability under effects of kaempferol, myricetin, and azaleatin in the HGC-27 cell line.
Selective pressure generated by the misuse of antibiotics in medicine and agriculture has resulted in antimicrobial resistance and the subsequent reemergence of several pathogenic bacteria, including Mycobacterium tuberculosis (MT), the etiological agent of tuberculosis (TB) disease. Increased resistance of MT to previously-effective antibiotics is associated with greater incidence rates and burden of TB disease. Novel approaches to infection mitigation must be explored if we are to attenuate the destructive force of this pathogen.