Researchers from the Seattle Children's Hospital Research Institute and Fred Hutchinson Cancer Research Center have discovered that the molecule chemotoxin, which is found in scorpions, binds specifically to tumor cells. By developing the molecule into a type of tumor paint,' surgeons could possibly target cancer cells more accurately during surgeries and decrease the chances of remission.
Researchers at Rockefeller University, Howard Hughes Medical Institute, and the National Cancer Institute, led by Michel Nussenzweig and his brother Andre Nussenzweig and their colleagues, have discovered this month that a protein, known as ATM has new and extraordinary abilities. Not only does it help repair breaks in the double-stranded structure of DNA in immune cells, but it also prevents genetic damage from being passed on when the cells divide. This new discovery could potentially influence future studies of cancers of the lymph and immune system, known collectively as lymphomas, as ATM has a crucial role in the life cycle of immune cells.
As if arthritis sufferers were not already disadvantaged, they also face slower rates of recovery following knee surgery. According to research announced this month at the Annual Meeting of the American Orthopaedic Society for Sports Medicine, being female and suffering from osteoarthritis are both risk factors for delayed recovery after knee arthroscopy.
Approximately one in every 400 children suffers from Type 1 Diabetes . However, a team of scientists from the University of Florida recently discovered that blood from the umbilical cord might contain stem cells that can help defeat this debilitating disease.
Although raised lymph nodes, or glands', are often associated with minor infections such as colds, they may also hold clues to the effect of treatment on each case of esophageal cancer. John Vincent Reynolds, a professor of surgery at the University of Dublin in Ireland, and his colleagues found that the success of treatment may be determined, in advance, by the presence of cancer cells in local lymph nodes. This is important as clinicians may now predict more accurately whether a patient is likely to survive after treatment for cancer of the esophagus.
Researchers from the Weizmann Institute of Science in Israel collaborated with the Department of Neurology at the University of Pennsylvania and the Department of Neuroscience at the University of Connecticut to investigate the types of cell-to-cell interactions that play a role in myelination. The results published this week in Nature Neuroscience reported that an interaction between two molecules on axons and "helper" Schwann cells is necessary for myelination, with important implications for the treatment of the host of human diseases affected by the loss of myelin.
A decade-long study of young children with brain tumors found that the use of chemotherapy instead of radiation therapy reduces the chances for long-term brain damage. Radiation therapy was previously believed to be the best treatment for brain tumors despite an increased risk for future learning difficulties. However, the study, conducted in the UK and published in Lancet Oncology, demonstrated that chemotherapy was just as effective and had fewer side effects on children's developing brains.
Chronic fatigue syndrome is finally gaining credibility now that the Center for Disease Control and Prevention has released studies linking the condition to genetic mutations and abnormalities in gene expression.
While many students of evolution are familiar with the story of the peppered moth, the most recent chapter of evolutionary theory has been written about a black butterfly. The butterfly species Hypolimnas bolina, H. bolina, has experienced "the fastest evolutionary change that has ever been observed", according to Sylvain Charlat, a post-doctoral researcher, who led a study published in Science earlier this month.
Scientists at the University of Edinburgh have found that the brains of people who suffer from continued episodes of bipolar disorder shrink at a progressively faster rate. This new insight into bipolar disorder shows that relapses of this life-long condition actually produce worsening changes in the brain, possibly affecting current treatments.
Children who are more resistant to peer influence have a higher level of interconnectivity in the regions of their brains that control certain behaviors, according to a study published July 25 in The Journal of Neuroscience.
Although all forms of cancer therapy aim to rid the body of malignant tumors, they are not always completely successful. Devastating side effects can occur, which can permanently effect the patient's quality of life Such life-altering side effects occur in many people who have undergone chemotherapy.
The nucleus of a cell is not sedentary, but occupies different locations in the cell at different times for different purposes. The proper migration and anchoring of the nucleus during development in polarized cells (e.g. neurons, muscle cells) becomes physiologically critical for signal transduction, structural integrity, and other functions in multicellular organisms.
Trials in Australia have suggested a way to both fight climate change and improve the fertility of carbon-depleted fields. According to new research findings by the New South Wales Department of Primary Industries, Agrichar, a black carbon by-product of pyrolysis, has tripled wheat yields when applied to fields in Australia. It has been newly hailed as the saviour of Australia's carbon-depleted soils, which have reduced yields due in part to limited amounts of the element.
The complete formation of nitrogenase is an essential part in understanding how the complex enzyme works and is essential for further manipulation and research of the structure. The exact formation process has yet to be determined, but it is hypothesized that models, containing gene deletions, derived using X-ray crystallographic analyses of nitrogenase structures, can provide snapshots of the formation process depending upon the deletion.
The research that will be presented in this paper concerns the synthesis and testing of a bimetallic homogenous catalytic system based on a tetraphosphine ligand system. The [Rh2H2(µ -CO)2(rac-et,ph-P4)]2+ homogeneous catalyst system discovered by G. G. Stanley's laboratory can be resolved into pure enantiomers and has been shown to be one of the best asymmetric hydroformylation catalysts for vinyl esters with 85% enantiomeric excess (ee) and 4:1 branched to linear regioselectivity for vinyl acetate (Stanley 2005).
Informal educational centers, such as museums and public aquaria, have looked towards interactivity as one way to make their exhibits more attractive and informative. In some institutions, such as aquaria, direct interaction with most of the specimens is impractical. However, touch-screen information systems may become an effective way to introduce interactive experiences to visitors.
By using principles of the creative design process, a series of low-level prototypes and user studies were created to inform the design of an information visualization technique that deals with the problem of visually representing information quality. Understanding and clearly representing information quality is an important step in overcoming the problems of "information overload", a term used to describe the problem of having stronger data collection than data processing techniques. The hypothesis was that illustrative rendering techniques would be an intuitive and effective means for the display of information quality in multidimensional datasets.
Dark energy, which is believed to be a cosmic energy density that is gravitationally repulsive and does not appear to cluster in galaxies, has been invoked to account for the recent measurement that the rate of the universe's expansion is accelerating. To better understand these phenomena, scientists utilize type Ia supernovae as calibrated candles. Lawrence Berkeley National Laboratory (LBNL) is developing the Supernova Acceleration Probe (SNAP), a space-based telescope that will be used to identify and measure supernovae.