Addition of Zinc, Manganese, and Iron to Growth Media Triggers Antibiotic Production in Bacterial Isolates From the Lower Atmosphere

doi:10.22186/jyi.32.2.7-11 Abstract | Introduction | Methods | Results | Discussion | Conclusions |Acknowledgements | References | PDF Abstract With the growing number of antibiotic-resistant pathogens, there is a need for new antibiotics. Bacteria within the order Actinomycetales produce the majority of known antibiotic compounds but harbor cryptic secondary metabolic pathways that likely produce thousands more antibiotics awaiting discovery. This has recently renewed interests in bioprospecting for novel Actinomycetales in underexplored […]

rClone: A Synthetic Biology Tool That Enables the Research of Bacterial Translation

doi:10.22186/jyi.32.3.7-12-19 Abstract | Introduction | Methods | Results | Discussion | Conclusions |Acknowledgements | References | PDF Abstract Understanding bacterial translation is of interest to many high school and college biology students, but hands-on research of this process has traditionally been inaccessible because of the expertise required for molecular cloning. There is also a need for more and better translational control elements that can be used for genetic circuits with […]

Should I Stay or Should I Lyse? Viruses Communicate to Make Decisions

When a virus infects a cell, it has an important decision to make – whether to kill the host (lysis) or to integrate its DNA into the host genome (lysogeny), entering a state of dormancy. This anthropomorphic view may not be far from the truth. A recent study by Zohar Erez and colleagues in Israel, […]

A Magic Treatment? Study Finds Psilocybin Reduces Anxiety and Depression in Cancer Patients

Cancer patients are known to develop clinically significant, long-term symptoms of depression and anxiety. In fact, one in four cancer patients has clinical depression and almost 40% meet the criteria for a mood disorder.1 However, a recent Johns Hopkins University study shows that hope may lie in psychedelic research. In this long-awaited study, published in […]

Not Your Average Knot

Chemists at the University of Manchester have produced the tightest knot ever created. Published earlier this month in the journal Science, the team led by David Leigh used techniques in synthetic chemistry to braid strands of different molecules into a structure with over eight crossings. The first synthetic chemical knot was created in 1989 by […]

Updated AlphaGo Ready to Beat World’s Best

Earlier this month, Google Deepmind chief executive Demis Hassabis revealed that their updated version of AlphaGo, a program capable of learning and playing the board game Go, has exhibited remarkable success against the world’s best Go players in online matches. Go, for many decades, has been the game to beat for many artificial intelligence (AI) […]

Microbes and Medicine: An Interview With Dr. Prameet Sheth

Finding a career that embodies your interests, goals and values is difficult. For some people that means long hours of discovery in a research lab. For others, the most fulfilling career focuses on interacting with the public, or teaching students. Clinical microbiology is a fascinating interdisciplinary career that masterfully  blends these three fields into one […]

Interview With a Reproductive Biologist: A Closer Look at the Life and Work of Dr. Anne Croy

Dr. Anne Croy is a professor in the Department of Biomedical Sciences at Queen’s University. She also holds a Canada Research Chair (Tier 1) in Reproduction, Development, and Sexual Function, which is reflective of the outstanding contributions she has made to the field of reproductive biology. While her current research interests lie with conditions that […]

World’s First CRISPR Clinical Trial

Oncologist Lu You’s research group at Sichuan University injected a patient with CRISPR modified cells on November 15, marking the first time CRISPR gene-editing has been tested in a human. The team delivered modified cells into a patient suffering from aggressive lung cancer as part of their clinical trial at the West China Hospital in Chengdu. […]

Lessons From The Lab Bench

Undeniably, admissions committees prioritize a few select factors in considering applicants for scientific PhD programs. Foremost among them are previous research experience, matching interests with research groups, and undergraduate coursework. After three years of undergraduate research, I have received my fair share of advice on positioning myself for graduate school from colleagues, advisers, and friends. […]


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