Features Archives - Volume 17

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REVIEW ARTICLE: Pathways and Pathology in Cell Nuclear Migration and Anchorage


Written by Dmitry Ratner

Introduction

The nucleus of a cell is not sedentary, but occupies different locations in the cell at different times for different purposes. The proper migration and anchoring of the nucleus during development in polarized cells (e.g. neurons, muscle cells) becomes physiologically critical for signal transduction, structural integrity, and other functions in multicellular organisms. Current studies show that failure of nuclei to migrate and anchor pr ...More »

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